Adipose Tissue-Derived Factors: Impact on Health and Disease

The impact of adipose tissue-derived factors on the hypothalamic-pituitary-gonadal (HPG) axis.

Adipose tissue produces factors, including adipokines, cytokines and chemokines which, when released, systemically exert endocrine effects on multiple tissues thereby affecting their physiology. Adipokines also affect the hypothalamic-pituitary-gonadal (HPG) axis both centrally, at the hypothalamic-pituitary level, and peripherally acting on the gonads themselves. Among the adipokines, leptin, ...

Editorial: Bone Marrow Adipose Tissue: Formation, Function, and Impact on Health and Disease

Enthusiasm surrounding bone marrow (BM) adiposity has accelerated in recent years, motivated by numerous factors: adipocytes are abundant within the BM, BM adiposity increases in diverse pathophysiological states, and BM adipocytes can exert diverse effects both within and beyond the skeleton. This diversity has attracted a broad cross-section of scientists to the field and we are delighted to ...

Cytotoxicity of Chitosan Derived from Shrimp for Bone Scaffold on Adipose Tissue-Derived Mesenchymal Stem Cells

Pericardial Adipose Tissue, Atherosclerosis, and Cardiovascular Disease Risk Factors

OBJECTIVE Pericardial adipose tissue (PAT), a regional fat depot that surrounds the heart, is associated with an unfavorable cardiometabolic risk factor profile. The associations among PAT, cardiometabolic risk factors, and coronary artery calcification (CAC) and abdominal aortic artery calcification (AAC) in African American populations have not been explored. RESEARCH DESIGN AND METHODS A t...

Functions of Adipose Tissue and Adipokines in Health and Disease

Francisca Lago1, Rodolfo Gómez2, Javier Conde2, Morena Scotece2, Carlos Dieguez3 and Oreste Gualillo2 1SERGAS Santiago University Clinical Hospital, Research Laboratory 7 (Molecular and Cellular Cardiology), Santiago de Compostela, 2SERGAS Santiago University Clinical Hospital, Research Laboratory 9 (NEIRID LAB, Laboratory of Neuro Endocrine Interactions in Rheumatology and Inflammatory Disease...